Phospho.ELM Result

a database of S/T/Y phosphorylation sites

Statistics:
	Instances	42.914
	Kinases	299
	References	3.657
	Sequences	11.224
	Substrates	8.698

C/EBP alpha (Transcription factor)

Seq-ID:

P49715 [Homo sapiens]

Download:

Interaction Network(s):

-

External Source(s):

Phosida

Phosida

MINT Interaction(s):

[show]

MINT-4791133 RUNX1_HUMAN
MINT-7720853 UBF1_HUMAN

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
RNA polymerase II transcription factor activity, enhancer binding, transcription factor binding, promoter binding		transcription from RNA polymerase II promoter, generation of precursor metabolites and energy, cytokine-mediated signaling pathway, interspecies interaction between organisms, positive regulation of transcription from RNA polymerase III promoter

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	21	PRPPMSSHLQSPPHAPSSAAF	MAPK1	14701740	LTP	0.41	MOD_ProDKin_1	-	-	0.85	-	low
S	21	PRPPMSSHLQSPPHAPSSAAF	MAPK3	14701740	LTP	0.41	MOD_ProDKin_1	-	-	0.85	-	low

C/EBP alpha (Transcription factor)

Seq-ID:

P53566 [Mus musculus]

Download:

Interaction Network(s):

STRING

External Source(s):

Phosida

MINT Interaction(s):

MINT-5225582 FOXO1_MOUSE

GO-Terms:

[show]

Molecular Function	Cellular Component	Biological Process
protein homodimerization activity, specific RNA polymerase II transcription factor activity, RNA polymerase II transcription factor activity, enhancer binding, transcription factor binding, promoter binding		positive regulation of gene-specific transcription from RNA polymerase II promoter, lung development, macrophage differentiation, transcription, cytokine-mediated signaling pathway, negative regulation of cell proliferation, white fat cell differentiation, cellular response to organic cyclic substance, urea cycle, embryonic placenta development, cell maturation, brown fat cell differentiation, liver development, positive regulation of fat cell differentiation, cellular response to lithium ion, negative regulation of transcription from RNA polymerase II promoter, mitochondrion organization

Conservation:

Click on table headers for sorting

Res.	Pos.	Sequence	Kinase	PMID	Src	Cons.	ELM	Binding Domain	SMART/Pfam	IUPRED score	PDB	P3D Acc.
S	193	PPPPPPHPHASPAHLAAPHLQ	CDK4	16537903	LTP	0.56		-	-	0.92	-	low
S	193	PPPPPPHPHASPAHLAAPHLQ	CDK6	16537903	LTP	0.56		-	-	0.92	-	low
T	222	TTMHLQPGHPTPPPTPVPSPH	GSK-3_group	10567568	LTP	0.45	MOD_GSK3_1	-	-	0.97	-	low
T	222	TTMHLQPGHPTPPPTPVPSPH	GSK-3_group	12668682	LTP	0.45	MOD_GSK3_1	-	-	0.97	-	low
T	226	LQPGHPTPPPTPVPSPHAAPA	GSK-3_group	10567568	LTP	1.00	MOD_GSK3_1	-	-	0.97	-	low
T	226	LQPGHPTPPPTPVPSPHAAPA	GSK-3_group	12668682	LTP	1.00	MOD_GSK3_1	-	-	0.97	-	low
S	230	HPTPPPTPVPSPHAAPALGAA	-	10567568	LTP	0.61		-	-	0.94	-	low